Factory supply Dexrazoxane cas 24584-09-6 CAS NO.24584-09-6

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When dextropropimine is combined with doxorubicin, it has a protective effect on the latter's cardiotoxicity, but the mechanism of its cardioprotection is not very clear. Dexpropimine is a cyclic derivative of EDTA, which is easy to penetrate the cell membrane through Chemicalbook. Experimental studies have shown that dextropropylimine is transformed into a ring-opening chelating agent in cells, which interferes with the formation of free radicals mediated by iron ions, and the latter is part of the cause of cardiotoxicity of anthracycline antibiotics.